Therapeutic Effects of “Phu Thao Khang – PTP” Solution in the Treatment of Vaginitis and Cervicitis Caused by Mixed Bacterial Infection

Abstract

This study evaluated the adjunctive effect of Phu Thao Khang-PTP solution on selected paraclinical outcomes in women with vaginitis and cervicitis caused by mixed bacterial infection. An open-label controlled clinical intervention was conducted in 60 sexually active women aged >18 years who were diagnosed with vaginitis and/or cervicitis at Tue Tinh Hospital from April 2025 to March 2026. Participants were allocated into a study group receiving daily genital cleansing with Phu Thao Khang-PTP plus one Polygynax vaginal capsule daily for 10 days, or a control group receiving Polygynax alone for 10 days. Outcomes were assessed at baseline (D0) and day 10 (D10) using cervical examination, vaginal discharge characteristics, Candida testing, and Gram staining. After treatment, the study group achieved higher rates of normalization of cervical findings (86.7% vs. 56.7%), Candida clearance (100% vs. 86.7%), Gram-positive bacterial clearance (96.7% vs. 83.3%), Gram-negative bacterial clearance (93.3% vs. 76.7%), and overall grade A response (83.3% vs. 56.7%). No adverse effects were observed. Phu Thao Khang-PTP combined with Polygynax may be an effective and safe adjunctive treatment for mixed vaginitis and cervicitis.