Beyond the Pentad: A Lethal Presentation of TTP with Multiorgan Involvement

Abstract

This case report discusses a 41 year-old female with no significant past medical history who developed thrombotic thrombocytopenic purpura (TTP) presenting with severe hemolytic anemia, thrombocytopenia, acute kidney injury, and neurological deterioration. Despite aggressive plasmapheresis, corticosteroid therapy, and supportive care, the patient’s condition rapidly worsened, culminating in multiorgan failure and death. This report highlights the critical importance of early diagnosis and intervention in TTP and discusses the clinical and laboratory parameters guiding management.