Efficacy of Low Level Laser Therapy Combined with Scalp Microneedling using Clobetasol Propionate 0,05% Solution for the Management of Androgenetic Alopecia

Abstract

Androgenetic alopecia (AGA) is the most common, affecting over half of men and women. Low-level laser therapy (LLLT) has been claimed as a safe devise-based modality for stimulating hair growth in men and women in AGA. LLLT promote hair growth. Although the mechanism is still unclear, it is postulated that this action is due to mitosis acceleration and may be due to the activation of follicular keratinocytes and stem cells. Microneedling is also known as collagen induction therapy. It has been proposed that the trauma generated by needle penetration in the skin induces dermis regeneration. This research aims to assess the effectiveness of LLLT combined with scalp microneedling in the management of AGA. Three adult patients with AGA were subjected to scalp microneedling using clobetasol propionate 0,05% solution plus LLLT for 25 minutes. The treatment was performed at monthly intervals. Results have shown statistically significant improvement after treatment for three months. Low-level laser therapy combined with scalp microneedling could be a safe and good modality for managing AGA as determined by the clinical.