Mental Health Disorders Due to Oxidant and Antioxidants Imbalance: A Literature Review Study

Abstract

Health is a significant thing in human life because it is one of the supports for human activity. By living a healthy life, everyone can be productive socially and economically to achieve their desired life goals. Oxidative stress is an imbalance between the cellular production of Reactive Oxygen Species (ROS) and antioxidant countermeasures. The high oxygen consumption and lipid-rich environment in the brain are thought to be highly susceptible to oxidative stress or redox imbalance. Various kinds of literature show accumulating evidence of implications for free radical-mediated pathology, altered antioxidant capacity, neurotoxicity, and inflammation in neuropsychiatric disorders. Oxidative stress contributes to the specific clinical symptomatology of complex and debilitating psychiatric illnesses. This complex and heterogeneous oxidative stress disorder negatively impacts the quality of life, morbidity or mortality, and cognitive function, known as depression. Oxidative stress has received much attention concerning psychiatric illness and has also been suggested as a contributing factor to depression.