Predictors of Success of Trabeculectomy Augmented With Tenectomy in Patients With Primary Open Angle Glaucoma: A Cohort Study

Abstract

Objective: To evaluate the effectiveness of trabeculectomy augmented with tenectomy in controlling the postoperative intraocular pressure (IOP).Study Design: Cohort Study. Place and duration of study: Eye department, Fazaia Ruth Pfau Medical College, Karachi from November 2022 to November 2023. Introduction: Trabeculectomy augmented with tenectomy has been a widely used surgical procedure for the treatment of primary open-angle glaucoma. The success of this procedure can depend on various factors, including patient characteristics, preoperative conditions, and surgical techniques. Understanding the predictors of success in trabeculectomy augmented with tenectomy is crucial for optimizing patient outcomes and informing clinical decision-making.In this cohort study, we aim to investigate the factors that influence the success of trabeculectomy augmented with tenectomy in patients with primary open angle glaucoma. By identifying these predictors, we can potentially enhance the effectiveness of this surgical approach and contribute to the management of primary open-angle glaucoma.Patients and Methods: 96 eyes of 84 adult patients with Primary open angle glaucoma were included in study after baseline demographic information of candidates meeting the inclusion criteria. Pre- and postoperative glaucoma assessment was done, namely IOP and cup-to-disc (CD) ratio were recorded and analyzed. Results: The mean preoperative IOP was 24.54mmHg, median 26mmHg, mode 26mmHg with 95%CI. Mean IOP of 17mmHg was recorded on first, second and third postoperative follow-ups with 95%CI. Mean IOP of 14mmHg was recorded on the final postoperative follow up with standard deviation of 1.004SD with 0.218069 of 95%CI. Conclusion: In conclusion, trabeculectomy combined with tenectomy is a safe procedure which reduced the mean IOP to less than 20mmHg and reduced the number of topical antiglaucoma medications from 3 drugs to one drug.