Investigating the Dynamics of Single and Dual Infection of Schistosoma Species: A Mathematical Modeling Perspective

Abstract

Schistosomiasis is a prevalent parasitic disease that poses significant challenges to effective control measures, particularly in the presence of dual infections. This paper presents a study that aims to investigate the underlying mechanisms of schistosomiasis transmission through mathematical modeling, focusing on the dynamics of both single and dual infections, as well as the interaction between different species or strains of Schistosoma parasites. Sensitivity analysis of the basic reproduction number, , reveals the substantial influence of parameters such as  and  on disease transmission. The findings highlight the crucial need for comprehensive management strategies that address the complexities of dual infections and target influential parameters to effectively reduce disease transmission and mitigate the impact of schistosomiasis in endemic areas.