Agentic Artificial Intelligence for Prior Authorization Workflows in Healthcare

Abstract

Healthcare systems worldwide face significant challenges in managing prior authorization processes, which often create administrative burdens, delays in patient care, and inefficient resource utilization across providers, payers, and patients. This article examines the transformative potential of agentic artificial intelligence in revolutionizing prior authorization workflows through intelligent automation, seamless system integration, and adaptive decision-making capabilities. The article explores comprehensive implementation methodologies that encompass multi-channel request processing, automated data validation and enrichment, rule-based decision engines, and dynamic routing systems that collectively streamline authorization processes from initial request through final determination. The article reveals that agentic AI systems can successfully integrate diverse healthcare data exchange protocols, including FHIR, EDI standards, and legacy system interfaces, while maintaining robust security, compliance, and quality assurance frameworks. Stakeholder impact analysis demonstrates significant benefits, including reduced administrative overhead for healthcare providers, improved patient access to timely medical services, and enhanced operational efficiency for payers through cost reduction and optimized resource allocation. Technical infrastructure considerations encompass scalable data exchange platforms, comprehensive monitoring capabilities, and security governance structures that ensure regulatory compliance and data protection. Case studies and performance metrics illustrate substantial improvements in processing efficiency, decision accuracy, and stakeholder satisfaction across diverse healthcare settings and authorization scenarios. Future implications include integration opportunities with emerging technologies such as machine learning enhancement, predictive analytics, and advanced clinical decision support systems, while addressing evolving regulatory requirements and industry-wide scalability considerations. The article suggests that agentic AI represents a paradigm shift toward more efficient, accurate, and patient-centered healthcare administration that can address systemic challenges while establishing foundations for continued healthcare innovation and improved care delivery outcomes.